The Importance Of Tetrabutylammonium Bromide (TBAB) (CAS No: 1643-19-2)

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Posted by Admin on August, 02, 2025

Tetra butyl ammonium bromide (TBAB) (CAS No: 1643-19-2) is a quaternary ammonium salt, which plays a great role in the two fields of science and industry. The compound has acquired additional importance in recent days due to the intricate structural properties of the compound and the number of applications it is used in various industries.

Tetrabutylammonium bromide (TBAB) (CAS No: 1643-19-2), having a chemical formula of (C₄H₉)₄NBr,is one of the solvents that is found to be very soluble in organic solvents and functions as a phase-transfer catalyst.

It has common uses in organic chemistry, electrochemistry, and high technologies. It cannot be avoided in any graduate or industrial laboratory due to its various capabilities in chemical reactions.

Chemical and Physical Properties

Tetrabutylammonium bromide (TBAB) (CAS No: 1643-19-2) boasts so many advantages, and one of the main advantages that makes this material so necessary is its high thermal and chemical stability. It is a white crystalline powder, and it is soluble in water as well as in highly polar organic solvents such as methanol, ethanol, and acetone.

It is of moderate volatility with temperature; its melting point is of the nature of around 103-106°C, and it is not generally volatile in normal circumstances. Tetrabutylammonium bromide (TBAB) (CAS No: 1643-19-2) is hygroscopic and can absorb some amount of moisture that may be present in the air, and this must be taken into consideration during storage of this chemical too.

Ionic compounds and the presence of the hydrophobic butyl side chains give a dual nature needed in the transfer of the reactants between an aqueous phase and an organic phase that most chemical reactions necessitate.

Phase-Transfer Catalyst

Phase-transfer catalysis (PTC), where Tetra Butyl Ammonium Bromide (TBAB) is used as the medium between immiscible media or materials, e.g., water and oil, during the chemical reaction, is possibly one of the greatest uses of Tetra Butyl Ammonium Bromide (TBAB) (CAS No: 1643-19-2).

This feature is applicable in elevating the reaction rates and yields, especially in cases where reactions occur in nucleophilic substitution reactions.

When one of the reagents is in the aqueous phase and the other is in an (organic) solvent, the Tetrabutylammonium Bromide (TBAB) (CAS No: 1643-19-2) drives the interchange of the two types of ions across the phase boundary and, thereby, allows the initiation of chemical reactions in an efficient manner.

This has entailed it being the choice insofar as operational pharmaceutical, agrochemical, and polymer sectors are concerned.

Organic Synthesis

A broad field of application appears with Tetra Butyl Ammonium Bromide (TBAB) (CAS No: 1643-19-2) due to its catalytic propensity. It is applicable in alkylation, oxidation, reduction, and polymerization.

The ability of the catalyst to increase the effectiveness of the response under low conditions excludes the use of too much heat or pressure; thus, the procedures end up being secure and low in energy consumption.

Tetrabutylammonium bromide (TBAB) (CAS No: 1643-19-2) is also green with a friendly approach to green chemistry, as reactions can be done under aqueous conditions in most cases rather than under extreme conditions as the use of a powerful solvent. This aligns with the modern sustainability goals in the chemical sector.

Safety and Handling Hints

Tetrabutylammonium bromide (TBAB) (CAS No: 1643-19-2) represents another product that should be handled and stored safely by following the recommended procedures.

Though mostly considered to be of low toxicity, it may become irritating when inhaled or when it comes into contact with the skin and eyes. Handling should take place with personal protective equipment (PPE) such as gloves and safety goggles.

It ought to be tightly capped in a cool, dry area, which is free from moisture. The appropriate disposal procedures must also be adopted to reduce the effects on the environment.

Conclusion

To sum up, the Tetrabutylammonium Bromide (TBAB) (CAS No: 1643-19-2) is a precious chemical that has a variety of purposes in several fields and industries. It is in its multifunctional use as a phase-transfer catalyst and organometallic reagent and as

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